Years later, even after the destruction of the Site 12 Marker created by Isaac, his mind was still not completely free from the Marker's signal. His mind was harvested for Marker knowledge, providing blueprints which EarthGov used to create Marker copies, while memory-erasing drugs were used to keep the Marker's influence on his brain in check.

After his contact with Marker 3A on Aegis VII resulted in him becoming a host for a self-replicating mental blueprint of the Markers, Isaac became stranded in space before he was found in a crazed state by an EarthGov ship.įor the next three years, Isaac was held in an asylum on Titan Station and was diagnosed with a unique form of dementia resulting in haunting visions of his deceased girlfriend, Nicole Brennan. In 2508, Isaac was part of an emergency maintenance team of the USG Kellion that was sent to the USG Ishimura to investigate and handle the ship's mysterious communications failure. Isaac Clarke was a former ship systems engineer who worked for the Concordance Extraction Corporation, and the protagonist of the Dead Space series. Earth Government Colonial Alliance ' Stick around.

Dead space 3 is awakened canon